Catechins

Definition:

Catechins are a sub-class of flavanols (and thus flavonoids, and broadly polyphenols) — the dominant polyphenolic compounds in fresh Camellia sinensis leaves — consisting of four primary forms: EGC (epigallocatechin), EGCG (epigallocatechin gallate, the most abundant), EC (epicatechin), and ECG (epicatechin gallate) — responsible for tea’s astringency, contributions to bitterness, and the body of its health-research profile, and transformed upon oxidation into theaflavins (the bright-orange-red compounds of black tea) and thearubigins (the dark-brown high-molecular-weight polymers) — with catechin concentration in tea inversely correlated with shade-growing, positively correlated with sun exposure and temperature, and highest in the first-flush apical buds. Green teas retain catechins largely intact; black teas convert them; oolongs are intermediate.


In-Depth Explanation

The four main catechins:

CatechinAbbreviation% of catechin total in green teaNotes
Epigallocatechin gallateEGCG50–80%The most studied; most astringent; most health-cited
EpigallocatechinEGC10–30%Significant antioxidant; less astringent than EGCG
Epicatechin gallateECG5–15%Contributes to astringency; smaller quantities
EpicatechinEC5–10%Lowest astringency; related to cocoa flavanols

All are flav-3-ols with the same basic catechin backbone; gallated forms (EGCG, ECG) bind more strongly to proteins and are more astringent than non-gallated forms (EGC, EC).

Catechin content factors:

  • Sun vs. shade: Direct sunlight dramatically increases catechin biosynthesis; shade-grown tea has 40–60% lower catechin content than equivalent sun-grown tea from the same cultivar
  • Altitude: Higher altitude → slower growth → different catechin/amino acid balance
  • Bush age: Younger plantation bushes (3–10 years) often have higher catechin concentration than older trees
  • Flush season: First-flush buds have the highest concentration per weight; catechin % increases in later flushes
  • Cultivar: Significant variation between varieties — some cultivars breed specifically for lower catechin for reduced astringency applications

Oxidation transformation: When the kill-green step is omitted or delayed and the leaf is allowed to wither and oxidise, endogenous PPO (polyphenol oxidase) enzymes catalyse the oxidation of catechins into:

  • Theaflavins (TF): Bright orange-red pigments; contribute to black tea’s briskness and brightness; lower molecular weight
  • Thearubigins (TR): Large dark-brown polymers; contribute body and depth; the dominant colour compound in black tea

This transformation from catechins → theaflavins/thearubigins is the fundamental biochemistry of black tea production.

Health research context: Catechins — particularly EGCG — are among the most studied phytochemicals for potential health applications:

  • Antioxidant capacity (free radical scavenging)
  • Anti-inflammatory properties
  • In vitro and animal studies suggest anti-cancer mechanisms (NF-κB inhibition, apoptosis induction in cancer cell lines)
  • Cardiovascular protection (LDL-cholesterol oxidation inhibition)
  • Antimicrobial activity (particularly against oral bacteria)

Clinical evidence in humans is mixed — supplemental doses show effects; normal tea drinking concentrations show correlations in epidemiological studies but causality is difficult to establish.


Research

Comprehensive catechin chemistry review:

Mukherjee, A., & Bhattacharyya, S. (2020). “Catechins in tea: biochemistry, health effects, and processing.” Comprehensive Reviews in Food Science and Food Safety, 19(3), 1125–1155.

EGCG health research:

Lambert, J.D., & Elias, R.J. (2010). “The antioxidant and pro-oxidant activities of green tea polyphenols: a role in cancer prevention.” Archives of Biochemistry and Biophysics, 501(1), 65–72.

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